Cherniy O. Bioelectrical activity of the brain in acute cerebral circulation disorders in conditions of pharmacological calcium channel blockade

The investigation object: bioelectric activity of brain of man in a norm and at the different forms of violations of cerebral circulation of blood. The investigation goal: to ground expedience of the use of pharmacological blockade of the calcium channel for renewal of functional activity of main brain after sharp violations of cerebral circulation of blood of different genesis. Methods of research: clinical, neurological and functional methods of research of CNS, electro-encephalography, method of integral quantitative analysis EEG, statistical methods. Theoretical and practical value of the obtained results. Efficiency of application of blockers of the calcium channels well-proven for renewal of electric activity of cerebrum after the strokes of different etiology. Expedience of the use in clinical practice of method of integral quantitative estimation is rotine EEG for description of functional activity of brain at violations of cerebral circulation of blood of different etiology. The mathematical models of ischemic and hemorrhagic strokes, which are the methods of evidential medicine and characterize the degree of weight of the state of patients, and also efficiency of measures on renewal of electric activity of cerebrum after strokes, are developed. The developed methodical approaches will find application at planning and leadthrough of researches on clinical physiology of CNS, and also in the process of development of monitoring of the state of patients with the features of cerebral circulation of blood. Can be drawn on the got results and exposed conformities to law in a pedagogical process at teaching of physiology, physiopathology, anesthesiology and intensive therapy, neurology, neuro-surgery. The exposed features of pathogenic correction can become basis for the improvement of charts of therapy of patients with sharp violations of cerebral circulation of blood of different etiology. Scientific novelty of the obtained results: First through the methods of evidential medicine the estimation of efficiency of the use of blocker of the calcium dustings is conducted at sharp violations of cerebral circulation of blood of different etiology. The degree of implementation: Materials of dissertation are inculcated in an educational process on the department of physiopathology of Donetsk Medical University the name of Maxim Gorki and department of anesthesiology, intensive therapy and medicine of the urgent states of Faculty of postgraduate education Donetsk Medical University the name of Maxim Gorki, separation of reanimation of DOKTMO.