Sydor Y. Dynamics of episyndrome in supratentorial cerebral tumors before and after surgery.

The work covers a new theoretically grounded solution of the problem of diagnosis and dynamics of episyndrome from appearance to diagnosis establishment. Based on an investigation of 400 cerebral tumor patients (of them 300 patients with episyndrome and 100 patients without episyndrome), surgical interventions depending on topical localization and histobiological tumoral structure have been studied. It has been established that in hemisphere cerebral tumors all types of episeizures are seen. They depend on lobular and intralobular tumoral localization. It conditions several types of seizures in the same patient. It has been shown that in supratentorial cerebral tumors the most common are generalized seizures and absences. Anaplastic astrocytomas prevail according to histologic structure, frontal and temporal tumoral lesions prevail according to localization. Patients' complex investigation (EEG, CT, MRT) allow specifying tumors localization, their prevalence; which is important for choosing surgical treatment tactics. Tutorial process localization has been proved to have influence on clinical course and treatment results. Post-operative period in patients with left localized tumor is more severe, there are more recurrent seizures (70.31%) than in right localized tumor (29.69%). One of the major causes of recurrent episeizures at postoperative period has been found out to be continuous tumor growth. Pathomorphologic and clinicomorphologic peculiarities of epileptogenic - epileptic complex in patients with supratentorial cerebral tumors considerably determine surgical treatment tactics - the degree of radical tumoral removal and cortex resection sizes in epileptic focus area. An algorithm for treating patients with supratentorial localization accompanied by episyndrome and recommendations for its use in therapeutic practice have been worked out.