Kulish S. Synthesis, transformation, physical-chemical and biological properties of S-derivatives 2,4-dihydro-4-R-5-(2-pyridil)-3H-1,2,4-triazol-3-thions.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U000637

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

19-02-2010

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The main aim of the dissertation was to synthesize of new high performance and low toxic compounds of high with potential antimicrobial, diuretic, analeptic, antiinflammatory, antioxidantic, immunostimulating, hepatotropic and neurotropic activities among the 5-(pyridin-2-il)-2H-1,2,4-triazol-3-thion and 4-phenil-5-(pyridin-2-il)-1,2,4-triazol-3-thion, and their S-derivatives, to establish the interconnection between their chemical structure and biological effect, to recommend of new effective drugs for clinical practice.

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