Kalushka O. Фармакогностическое исследование пырея ползучего (Agropyron repens (L.) Beauv)

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U001979

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

02-04-2010

Specialized Academic Board

Д64.605.01

Essay

Pharmacognostical research of ground and underground parts of the the couch-grass - has been conducted. The qualitative structure was investigated, and quantitative content of basic biologically active substances of primary (polysaccharides, amino acids, ascorbic and organic acids, carotenoids, chlorophylls, adipose acids) and secondary (tannin, flavonoid, hydroxycoric acids, saponins, ethereal oil) synthesis was determined. The cell structure of grass together with rhizome and root of the raw materials under study was defined. According to the research there are 4 macroelements and 11 microelements.The structure of 7 individual substances of phenological origin educed out of the couch-grass were determined: 4 derivatives of choric acid (caffeine, ferula, chlorogenic, neochlorogenic) and 3 derivatives of 2-phenolbenzo-?-pyrene.Morphological-anatomical study of ground and underground parts of the couch-grass was conducted, their main numeral indices were defined on the basis of which the project ASD 'The Weed of the Couch-grass' and 'The Rhizome and the Root of the Couch-grass' was worked out. Thick extracts were received from the weed of couch-grass, their pharmacological activity (anti-inflammatory and hepatoprotective) was determined. Antibacterial action of the extracts from the weed, rhizome and root of the couch-grass was investigated on three strains of bacteria: Pseudomonas aeruginosa, Escherichia coli and Bacillus subtilis.

Files

Similar theses