Grytsaі V. The influence of infectivity of prostatic gland by pathogens of various taxonomic origin on the course of illness and the results of surgical treatment of patients having benign prostatic hyperplasia

The dissertation solves the actual problem of urology that lies in advancing the quality of diagnosis in infectious impairment of prostatic gland in patients with benign prostatic hyperplasia (BPН) through identification of pathogens of sexually transmitted diseases (PSTD) in genital excreta and in the prostate gland tissue, determination of the influences of these pathogens on the clinical course of a disease and the appearance of early postoperative prostatectomy complications.Тhe investigation included 101 patients with BPН aged from 50 to 86 years. By means of polymerase chain reaction of urethral scrapes, prostatic secretion and prostatic tissue removed intraoperationally, 53.5% of patients demonstrated the DNA presence of PSTD. It was proved that in 92.6% of infected patients with BPН there was noted discrepancy in results of studying of the genital excretes and prostatic tissue for PSTD. It was stated that the chronic inflammatory process in prostatic glant and urethra in BPH patients without signs of urinary infection was mostly stipulated by pathogens of ureaplasmosis and trichomoniasis, and statistically significantly enhanced the expressiveness of symptoms of the lower urinary ways. It was firstly proved that the infectivity by PSTD and the chronic inflammatory process in prostatic gland and/or urethra in BPH patients statistically significantly elevated the frequency of early postoperative complications of prostatectomy.There was scientifically substantiated the necessity of perioperative identification of the indicated group of pathogens that allows to adequately plan the conservative and perform prophylactics of complications of surgical treatment for this category of patients