Chujkova V. Thyroid gland dysfunction and its correction ways with cryopreserved placental tissue

The research object. Viability of the samples of endocrine material, stored at -196°C for 5 years as well as comparative morphological characterization of some inner organs of recipient animals and biochemical indices of blood serum during the correction of experimental hypothyreosis by means of subcutaneous introduction of the fragments of cryopreserved xenogeneic fetal thyroid gland, cryopreserved allogeneic placenta and their combined introduction. The research aim. Hypothyreosis correction by means of subcutaneous introduction of the fragments of cryopreserved allogeneic placenta and its combined introduction with the fragments of cryopreserved xenogeneic fetal thyroid gland. Research methods. Cryobiological, biochemical, immune enzyme, histological, morphometrical and statistical. For the first time the effect of subcutaneous introduction of the fragments of cryopreserved allogeneic placneta on the state of thyroid gland, liver parenchyma and thymus of the animals at experimental hypothyreosis has been studied. For the first time there was demonstrated the difference of the effect of introduced biological material on the state of inner organs of recipient animals.