Belokobylskiy S. Influence of peptidoglycans, lipopolysaccharides and bacterial exotoxins on metabolism and production of antibodies by B cells in vitro

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U004738

Thesis Registration Form

0410U004738.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

05-11-2010

Specialized Academic Board

Д29.600.02

Essay

The thesis is devoted to the clearance of the influence in vitro of peptidoglycans, lipopolysaccharides and bacterial exotoxins on metabolism and production of antibodies by B cells. For the first time the influence of staphylococcal, diphtheritic and tetanic toxins and also of peptidoglycans, lipopolysaccharides on the lipid peroxidation,activity of antioxidant enzymes, systems of cyclic and adenyl nucleotides, antibody production by B cells is studied in vitro. It is shown that bacterial derivatives have species and dose-dependent influence on metabolism of B cells at their direct contact in vitro.

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Files

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