Yatsenko K. Influence of intermittent normobaric hypoxia on the state of CNS and cerebral circulation of blood for the children with cerebral pathology.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U005553

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

21-09-2010

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

Thesis is devoted to researching of possibilities of intermittent normobaric hypoxia (INH) application for the acceleration of proceeding in the physiology functions of central nervous system and cerebral blood flow for children with a cerebral palsy (CCP). Got results was allowed to make a conclusion, that after the conducted course of therapy with application of ІNH a positive dynamics, which was marked in the state of locomotory status of children, appeared the certain higher, than for patients which treated oneself on a traditional chart. The positive changes of spectral constituents of electroencephalogram were more expressed and reliable in children with CCP, before the complex treatment of which ІNH entered. Comparison of results, got during realization of Doppler angiography research of patients of both groups, showed that for children which ІNH was conducted, a positive dynamics of Doppler angiography of brain patterns, which characterize middle speeds of blood flow, was for certain more significant. The same can be said and about the dynamics of indexes which characterize the state of eyegrounds for the inspected children from CCP. The substantial improvement of the state of organism resistance, certain on the indexes of leukogram, was marked for patients to traditional treatment of which added ІNH. It was set a diminishing of number of unfavorable adaptation reactions: decreasing of the percent of hyperactivation reactions, chronic and sharp stress. The analysis of the obtained data grounds to assert that including to complex therapy of patients with CCP of INH method increases efficiency of treatment, positively influences on the clinical flow of disease.

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