Kutsak A. Diagnostics and treatment of non-motor disorders in Parkinson's disease.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U000992

Applicant for

Specialization

  • 14.01.15 - Нервові хвороби

24-03-2011

Specialized Academic Board

Д 26.613.01

Shupyk National Medical Academy of Postgraduate Education

Essay

Dissertation is devoted the improvement of methods of early diagnostics on the basis of complex examination and increase efficiency of treatment of non-motor disorders in Parkinson's disease (PD). In-process first certainly, that the level of neuron-specific enolase (NSE) of more than 30 мg/L is associated with the high estimations of non-motor manifestations of PD, in a greater degree cognitive disorders. It is set from data of regressive analysis, that the presence of non-motor manifestations influences on life quality in patient with PD, expressiveness of depressions and pain syndrome. As a result of the conducted research the original discriminant model of neuro-psychological examination is offered with a high sensitiveness which allows it is enough exactly to diagnose and determine authenticity of unfavourable clinical course of PH, and also in good time to develop strategy, with the purpose of diminishing of progress of pathological process and prevention complication.

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