Didyk N. The effect of bisoprolol and sotalol on the structural and functional statys of cardiovascular system in the patients suffering from the hypertension disease and extrasystolia

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U003557

Applicant for

Specialization

  • 14.01.11 - Кардіологія

11-05-2011

Specialized Academic Board

Д 20.601.01

Ivano-Frankivsk national medical university

Essay

120 patients with arterial hypertension and frequent extrasystolia (E) without significant heart failure were included into the study. Ventricular and combined E was associated with unfavorable blood pressure profile as well as higher enddiastolic left ventricular volume, diastolic dysfunction, aortic valve fibrosis, aorta remodeling, endothelial dysfuction and more prominent lipid disorders. Superventricular E was associated with hypertriglyceridemia, left ventricular diastolic dysfunction and left atrium enlargement. Bisoprolol was less effective in E reduction comparing to sotalol, but higher antihypertensive and antiischemic effects.

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