Zatylnikova O. Pharmacognostic study of Iris pseudacorus L.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U005018

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

08-06-2011

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

For the first time complex phytochemical research of leaves and rhizomes of Yellow Iris was carried out. For the first time 37 compounds were isolated. From the rhizomes of Iris a new natural compound was isolated and its structure was determined as 5,6-dihydroxy-7,8,3',5'-tetramethoxyisoflavon. For the first time 32 volatile compounds, 14 fatty acids, 16 elements were identified. In leaves and rhizomes of Iris quantitative polysaccharides, polyphenolic compounds, flavonoids, isoflavonoids, hydroxycinnamic acids, the summ of ?-pirons, organic acids, chlorophylls, carotenoids were quantitatified. The main anatomical diagnostic and histochemical characteristics of of Iris have been determined. The technology of obtaining of biologically active complexes from the leaves and rhizomes of Iris has been developed. On the base of pharmacological research it has been established that extracts have anabolic, adaptive, antihypoxic, antimicrobial, immunomodulatory and diuretic activity. The following draft sets of monographs for the medicinal plant drugs “The rhizomes of the Yellow Iris”, “The leaves of the Yellow Iris”, “The dry extract of rhizome of Iris”, “The dry extract of the leaves of Iris”.

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