Ivanov Y. Features of the regeneration of knee cartilage in rats after cryotherapy and the application of low-molecular fractions of cord blood of cattle

The object of research is reparation of grassers of cartilage of knee-joint of rats after traumatic damage.The research purpose - to study the features of repararation on the model of osteohondrous defect after cryoinfluence, combined with the use of low-molecular faction (to 5 kDa) of cord blood. Methods: biochemical, histological, histochemistry, biomechanics, roentgenologic and statistical methods. It is established, that application low-molecular fraction (up to 5 кDа) cord blood or cryoinfluence, and also their complex use promotes accumulation in regenerate components of matrix. It is shown, that application of low-molecular fraction (up to 5 кDа) cord blood or cryoinfluence, and also their complex use promotes restoration of morphological composition and functional activity and reduces the area of defect in a cartilage of experimental rats.