Smyrnova M. Pathogenesis of posttraumatic epilepsy genesis in remote terms after a mild head injury

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U005538

Thesis Registration Form

0411U005538.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

22-06-2011

Specialized Academic Board

Д 29.600.02

Essay

The thesis is devoted to the study of pathophysiological mechanisms of posttraumatic epi-lepsy genesis in remote terms after a mild head injury. We used clinical, neurophysiological, neurovisualization, biochemical, and statistical methods. It was educed that an epileptic syn-drome was formed in 8 months - 3 years after a trauma and was polymorphic on its structure. Correlation of character of epileptic syndrome with hemodynamic, electro-encephalography, structural traits, energy balance, and status of freely-radical oxidization of lipids has been found. New method was designed to treatment of posttraumatic epilepsy by use of topamax and kortexin combination.

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