Suvorov O. Production of salts of 3-(4?-acetylphenylcarbamoyl)-propionic acid and standardization of hemostatics on their basis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U007089

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

07-12-2011

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The thesis is devoted to the synthesis of the new biological active substances on the basis of salts of 3-(4'-acetylphenyl-carbamoyl)-propanoic acid and standardization of haemostatic on their basis. Salts of 3-(4'-acetylphenylcarbamoyl)-propanoic acid with cations of organic bases, which are stable to hydrolysis, were implemented and their haemostatic actions were proved. The method of synthesis of substance of original hemostatic «Succiphenat» was scientifically grounded and standardized and methods of quality control of substance and lyophilized powder of succiphenat were developed.

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