Kasiyan O. Hygienic assessment of influence of environmental factors on the autoimmune thyroiditis prevalence among the inhabitants of Lviv region

The Dissertation deals with the studies of the environment factors influence on the prevalence of autoimmune thyroiditis among population of Lviv region. To determine its non-homogeneity as to the iodine content in drinking water; correlation between the iodine concentration in water in areas with different level of iodine-sufficiency and antibody titers to thyroglobulin and thyroperoxidase. The most substantial influence on the thyroiditis development among the adult population is stipulated by total beta-activity of drinking water and Cs137 specific activity in foodstuffs; among teenagers - chemical pollution of food products, Sr90 specific activity in food and atmospheric precipitation; among children - chemical pollution of food, water, soil and Cs137 level in drinking water. The relative risk of thyroiditis development proved to be much higher among people that inhabits the regions low-iodine content and much more polluted environment. In order to decrease the risk of autoimmune thyroiditis the differential approach in iodine-deficient prophylaxis is needed; with due regard for median ioduria, iodine endemia level, the state of environment and peculiarities of wide-spreadness of thyroiditis among some separate age and sex groups of population.