Sukhomlyn A. Influence of omeprazole-induced hypergastrinemia on salivary glands of rats and its correction

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U001107

Thesis Registration Form

0412U001107.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

23-12-2011

Specialized Academic Board

Д29.600.02

Essay

The point has been proved that the leading role in the development of pathological changes in tissues of salivary glands subject to long-term omeprazole treatment play disturbances in synthesis of regulatory polyamines, misbalance of NO-ergic system, activation of oxidative stress, oppression of antioxidant systems, development of endogenous intoxication, decompensation of proteinase-inhibitory potential. Per oral use of multiprobiotic of the last generation "Symbiter acidophilic" has had a positive compensatory influence on tissues subject to long-term omeprazole treatment

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