Vovk A. Influence of salmonella toxins on secretory activity and metabolic status of human blood monocytes and neutrophils in vitro

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U001518

Thesis Registration Form

0412U001518.pdf

Applicant for

Vovk Aleksandra Olegovna

Specialization

14.03.04 - Патологічна фізіологія

Date of defense

10-02-2012

Specialized Academic Board

Д 29.600.02

Essay

The thesis is dedicated to the study of salmonella toxins influ-ence on secretory activity and metabolic status of human blood monocytes and neutrophils in vitro. For the first time the S. сhol-erae-suis lipopolisaccharide and enterotoxin ability to stimulate se-cretion by monocytes and neutrophils of interleukins-1, -6, -8, tumor necrosis factor, prostaglandin Е2 and leukotriene С4, to inten-sify processes of lipid peroxidation, to inhibit the activity of antioxi-dant enzymes and to modulate the intracellular contents of cyclic and adenyl nucleotides is established.

Thesis supervisor

Gaidash Igor Slavovich

Official opponents

Пустовий Юрій Григорович
Крюк Юрій Якович

Files

aref.doc

diss.doc

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