Lantukhova N. Glycemia control during the intra-operative period with the patients with type 2 diabetes mellitus

The thesis presented a generalization and a new solution to an actual scientific problem - the stabilization of carbohydrate metabolism in patients with type 2 diabetes based on the study of carbohydrate metabolism depending on the activity of the sympathoadrenal system and develop an optimal method of anesthetic management, depending on the degree of compensation for type 2 diabetes. Found that the total dose of insulin for the anesthesia and the average speed of its introduction, increase with the deterioration compensation SD.Klofelin dose of 2,16 ± 0,68 mg / kg, inhibits nociceptive impulses and the activity of the sympathoadrenal system, which reduces the severity of insulin resistance in patients with subcompensated decompensated and carbohydrate metabolism. Through this facilitated glycemic control and reduces the required rate of insulin. Clonidine at a dose of 2,16 ± 0,68 mg / kg, consisting of sedation, does not cause the development of hypotension and tachycardia alerts in response to tracheal intubation.