Stepanovichus O. The optimization of diagnosis and treatment of infertility in women with the external genital endometriosis

The dissertation is devoted to the pertinent problem of improvement of the results of treatment of infertile females with external genital endometriosis by optimizing diagnosis and combined correction of the additional factors of the infertility. There were determined the factors of infertility among the females with external genital endometriosis. The evaluation of the functional state of the immunity of the females of risk group was conducted. The complex of intraoperative antiadhesive prevention with the administration of sodium aminodihydrophtalasindion in the complex post-surgery treatment allows to decrease the relative risk of pain syndrome occurrence and relapses (RRR=0,22 with CI 95% (0,18; 0,25)). The developed diagnostic-treating algorithm for the clinical management of the patients with external genital endometriosis consider to use the treating-diagnostic laparoscope with the administration of low-dose monophase combined estrogen-gestagen medication containing dienogest and sodium aminodihydrophtalasindion in the post-surgery period with active expectant management with controlled ovarian stimulation leads to improving reproductive results.