Iakovenko V. Optimization of endoscopic diagnosis and treatment of gastric mucosa metaplasia and dysplasia

Results of analysis of esophagogastroduodenoscopy accomplished to 284 patients with dyspeptic complaints are presented. Introduction of methods of high-resolution, high magnification (up to 115), narrow-band imaging videoesophagogastroduodenoscopy combined with chromoendoscopy techniques and precision biopsy has allowed to increase (in comparison with routine fibroesophagogastroduodenoscopy) study sensitivity from 37.5% to 70.9% (p<0,05); the proportion of initial verification of gastric mucosa atrophy, metaplasia and neoplasia, respectively, in 18 (p = 0.0001), 10 (p<0.05) and 3 (p = 0.045) times. Endoscopic mucosal resection characterized by short hospitalization (2.2 days, sygma ±1,1) and low complications. Precancerous changes of gastric mucosa screening algorithm give the opportunity to optimize diagnosis and treatment of metaplastic and dysplastic gastric mucosa results.