Brytanova T. Synthesis, chemical and biological properties of derivatives of 4-benzylidenamino- and 4-(furan-2-ylmethylenamino)-1-R-4H-1,2,4-triazolium halogenides.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U003044

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

11-05-2012

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The aim of this work was synthesis of new highly effective and low toxic compounds with potential diuretic, antimicrobial, antifungal, neurotropic, anti-inflammatory and hypolipidemic activity among derivatives of 4-benzylidenamino-1-R-4H-1,2,4-triazolium halogenides and 4-(furan-2-ylmethylenamino)-1-R-4H-1,2,4-triazolium halogenides, evaluation of their "chemical structure - biological activity" correlation, and also selection and recommendation of the most active compound for preclinical trial.

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