Guzenko N. Development methods of analytical diagnostics of ketamine poisoning

Thesis is based on research of narcotic drug chemic-toxic effect of ketamine. The first attempt of comparing analysis method to isolate ketamine from biological substances methodics applied for forensic toxicology. Studied many methods to separate protein from blood, suitable for HLPC analysis. Established, international (TIAFT) and local systems for screening toxic substances realizing by thin layer chromotography method to identify ketamine is impossible. Have been offered selective system for identify ketamine by thin layer chromotography method while available other illicit drugs. Pretreatment gas-liquid chromatography method to identification and determination of ketamine in biological material. Have been studied chromatographic characteristics of ketamine and condition microclumn HLPC - analyzator and shows possibility of identify ketamine contains above drugs. The algorithm of design of research is made for forensic and clinical toxicology to identify and determine ketamine in biological materials or liquids of human organism.