Kozlovska T. Optoelectronic device for diagnostics of the state of peripheral blood circulation with increased validity

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U003878

Applicant for

Specialization

  • 05.11.17 - Медичні прилади та системи

31-05-2012

Specialized Academic Board

Д 05.052.02

Vinnytsia national technical university

Essay

A research object is the processes of optical radiation interaction with biological tissues during the diagnostics of peripheral blood circulation by optical-electronic devices for diagnostics of peripheral blood circulation; the purpose of work is an increase of diagnostics validity of the state of peripheral blood circulation by the improvement of methods of optical radiation registration and application of optical-electronic devices for diagnostics of peripheral blood circulation; research methods are based on the substantive provisions of theory of transfer of radiation for description of processes of optical radiation interaction with biological tissues, mathematical modelling - for research of the change intensity of optical radiation, methods of filtration - for the removal of base-line noises, methods of functional synthesis - for the modelling of optical-electronic charts, mathematical statistics and computer processing of information - for verification of adequacy of the developed models; theoretical results - first a feet-hand criterion is experimentally got for patients with the chronic ischemia of lower extremities by a photoplethysmographyc method which determines correlation of signal amplitude of sick extremity to amplitude of healthy individually for everybody, that allowed to promote the diagnostics validity. The standard masks of photoplethysmographyc signals are first got due to the use of veyvlet-transformation method for determination of degree of peripheral blood circulation violation. Physicomathematical model of optical radiation difusion in biological tissues is improved, which differs that takes into account a change intensity of optical radiation depending on the corner of establishment of optical touch-control and index of ekstinktion. The simulation method Monte Carlo is improved, which differs that takes into account the loss of energy of photon due to a diffuse reflection, that allows to determine the effective depth of penetration of optical radiation; practical results - the algorithmic and program providing of imitation modeling of distribution of optical radiation is developed in biological tissues on the basis of method Monte Carlo. The algorithmic and program providing of treatment of photoplethysmographyс signals is developed on the basis of Fourier-transformation. The algorithmic providing of removal of base-line noises of photoplethysmographyс signals by veyvlet-transformation. The structure of optical-electronic device for diagnostics of the state of peripheral blood circulation is improved due to the use of four optical sensors and introduction of standards block. Degree of introduction - disertacion performances are inculcated on the base of research and production medikal-biological corporation "Laser And Health", (Kharkov, Ukraine) and in the educational process of department of laser and optoelectronic technology of the Vinnytsia National Technical University.

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