Nazemets T. Clinical and prognostic role of plasma N-terminal pro B-type natriuretic peptide in heart failure.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U004953

Applicant for

Specialization

  • 14.01.11 - Кардіологія

19-11-2012

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The basis of the data are of clinical and instrumental examination of 141 patients with chronic heart failure (CHF) II-IV NYHA status. NT-proBNP level were measured buy immunoenzyme method at first hospitalization day and at discharge day. Long - term survival in patients with CHF NYHA II-IV classes depend on NT-proBNP. Cumulative survival in patients with CHF III-IV NYHA classes after therapy depend on a decrease NT-proBNP over a period in-hospital treatment. Patients with CHF caused hypertensive heart and preserved LVEF ((? 40%), treated with beta- blocker and ACE inhibitor is possible to recommend aliskiren addition which improve left ventricle diastolic filling and reduce NT-proBNP plasma level.

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