Prokofyeva N. Optimization of treatment of urticaria based on pathogenesis and severity of the dermatosis.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U004985

Thesis Registration Form

0412U004985.pdf

Applicant for

Specialization

  • 14.01.20 - Шкірні та венеричні хвороби

15-11-2012

Specialized Academic Board

Д. 26.003.02

Essay

Dissertation is devoted to scientific problem solution of optimization of treatment of patients with chronic urticaria by studying clinical features and pathogenetic mechanisms of the disease. It was determined that patients with chronic urticaria have increased levels of free radical oxidation products - malonaldehyde and diene conjugates, increased activity of hydrolytic enzymes elastase and urease and increased content of total IgE. In patients with chronic urticaria decreased content of antioxidant enzymes - catalase, superoxide dismutase, glutathione peroxidase and antimicrobial enzyme lysozyme were also detected. Optimized method of complex therapy of patients with chronic urticaria using "Quercetine" provided clinical efficiency, positive dynamics of normalization of biochemical parameters.

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Files

aref.doc

Дисертація_ листопад 2012 (2).doc

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