Litus I. Optimization of tactics for managing patients with skin tags

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number


Applicant for


  • 14.01.20 - Шкірні та венеричні хвороби


Specialized Academic Board

Д 64.603.01

State institution "Institute of Dermatology and Venereology of NAMS of Ukraine"


The object of study is fibroepithelial polyps (FEP) of the skin. The aim is to optimize the management of patients with multiple recurrent skin FEP by developing the differentiated approach to their examination, prediction of recurrence and treatment, taking into account the morphological, immunohistological structure of polyps and metabolic status. Methods: clinical, biochemical, morphological, immunohistochemical, statistical. The dissertation is devoted to the study of clinical variants, concomitant pathology, recurrences, morphological structure of the polyp, metabolic status in patients with multiple recurrent skin FEP to improve their diagnosis and treatment. Patients with skin FEP have a significant increase in the risk of developing metabolic syndrome. Total cholesterol, triglycerides, lipoproteins, atherogenic factor, blood glucose, glycosylated hemoglobin, insulin, C-peptide, HOMA-IR index, and leptin were significantly higher in patients with multiple recurrences. Predictors of recurrence were established and a Score scale was formed to predict recurrences of skin FEP. The developed diagnostic algorithm and the proposed treatment regimens for patients with skin FEP and concomitant metabolic syndrome significantly reduced the risk of recurrence. The results obtained by the author are implemented in practice: MNE "Kyiv City Clinical Dermatological and Venereological Hospital", MNE "Kirovograd Regional Dermatological and Venereological Dispensary", Ternopil Regional Dermatological and Venereological Dispensary, LLC "Institute of Psoriasis and Psoriasis and Chronic Dermatoses”, Municipal Institution “Rivne Regional Dermatological and Venereological Dispensary". The results of the dissertation are introduced into the pedagogical process of the Department of Dermatology and Venereal Diseases of Uzhhorod National University, the Department of Infectious Diseases with Epidemiology, Dermatology and Venereal Diseases of I. Horbachevsky Ternopil National Medical University. Area of use – dermatovenereology.


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