Yanovska K. Features of endocrine activity of adipose tissue and endothelial function in hypertensive patients with metabolic syndrome

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U005275

Applicant for

Specialization

  • 14.01.11 - Кардіологія

25-06-2012

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The basis of the data are of clinical and instrumental examination of 127 patients with hypertension and metabolic syndrome. We prove the necessity of determining the ratio of leptin/adyponektin, along with determination and IMT, endothelial function, as an additional surrogate marker of coronary atherosclerosis and diagnosis of high cardiovascular risk. The possibility of normalization of blood pressure and correction of surrogate markers of atherosclerosis patients with hypertension and metabolic syndrome should prefer a fixed combination of amlodipine and atorvastatin.

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