Selivanov S. Indications, an estimation of efficiency of prolonged sanitation of an abdominal cavity with peritoneosorbtion and phagotherapy in the complex treatment of patients with acute peritonitis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U000159

Applicant for

Specialization

  • 14.01.03 - Хірургія

19-12-2012

Specialized Academic Board

Д 11.559.01

Essay

The object of study - acute peritonitis of the abdominal cavity; The Aim - to improve the results of treatment of patients with acute diffuse peritonitis by objectification indications sanation by means of correlation of morphological structures of the peritoneum, the optimization method of intra-and postoperative sanation of abdomen by using of adapted bacteriophages and sorbents; Methods: general clinical, biochemical, laboratory, bacteriological, instrumental, histological, histochemical, immunomorphological, morphometric, statistical methods of examination; Novelty - Indications, character, duration of programmable sanation of abdomen, conduct and performance criteria compared with morphometric parameters parietal peritoneum; First performed morphological and functional assessment of tissue elements parietal peritoneum and microbiocenosis of exudates of the abdomen in acute peritonitis in conducting intra-and postoperative sanation of the abdominal by adapted bacteriophages, sorbents; The differential method of sanation of the abdomen by adapted bacteriophages in patients with acute peritonitis was approached; Result - A complex therapy of acute diffuse peritonitis, which includes developed a way to intra-and postoperative sanation of abdomen, has reduced by almost 1.2 times the number of relapses abdominal infection, reduce the number of complications from 56.4% to 32.4% reduce mortality from 28.3% to 16.4%; аll the methods are introduced in a medical practice, educational process;branch-medicine.

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