Iurchenko I. Chemical toxicological investigation of Nimesulide

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U000223

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

18-01-2013

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The thesis deals with chemical toxicological investigation of nonsteroidal anti-inflammatory drug Nimesulide. For the first time a phased scheme of chemical-toxicological analysis of biological material for Nimesulide content is developed on the basis of experimental data of the dynamic changes in the content of Nimesulide in cadaveric liver, which is to improve the accuracy and reduce the time of the study, as well as to determine the content of the drug in vivo that provoked poisoning.

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