Volochai V. The pharmacognostic research of plants of genus Galinsoga Ruiz et Pav of Ukrainian flora

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U000412

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

21-01-2013

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

Complex pharmacognostic research of plants of the genus Galinsoga Ruiz et Pav of Ukrainian flora was carried out for the first time. Different groups of biologically active substances in plant raw material of gallant soldier and shaggy soldier were identified and quantified. 15 amino acids, 19 macro- and microelements were found in herb of both species. 32 and 31 organic acids, 74 and 61 components of the essential oil were identified in their plant raw material respectively. The extraction and chemical research of water-soluble polysaccharide complex of herb of gallant soldier were carried out. 14 phenolic compounds were isolated from herb of gallant soldier in individual state and their structure was determined. Main morphological and anatomical diagnostic characteristics of herb of gallant soldier and the differences between species of genus Galinsoga Ruiz et Pav of Ukrainian flora were established. Technologies of obtaining of analgesic, anti-inflammatory, diuretic and hepatoprotective pharmaceutical substances of herb of gallant soldier were developed. The following drafts of quality-control technology were developed on herb of gallant soldier and pharmaceutical substances.

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