Borzenkova L. The condition of cerebral circulation and clinical and neurological characteristics of patients with high cardiovascular risk

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U002652

Applicant for

Specialization

  • 14.01.15 - Нервові хвороби

18-04-2013

Specialized Academic Board

Д 26.613.01

Shupyk National Medical Academy of Postgraduate Education

Essay

The dissertation focuses on improving of diagnosis and treatment of patients with chronic cerebral ischemia which combined hypertension and early manifestations of atherosclerosis with high cardiovascular risk. It has been found that the leading clinical neurological syndroms in chronic brain ischemia patients combined hypertension and early manifestations of atherosclerosis with cardiovascular risk on the SCORE<5% scale are cephalgic and autonomic dysfunction syndrome, and in patients with cardiovascular risk on the 5%<=SCORE<10% scale - a vestibular-atactic syndrome more ofen. А thorough study has revealed the presence of rheological properties of blood with an increase in cardiovascular risk. Confirmed the hypothesis of a relationship changes vegetative status according to the heart rate variability (HRV) on the severity of CWR. Determination of the LF / HF ratio in patients with chronic brain ischemia when combined hypertension and early manifestations of atherosclerosis with cardiovascular risk, that indicate a shift of autonomic balance toward sympathetic dominance influences the nervous system and significant decrease with increasing degree of CWR statistics SDNN, which correlate progression of cognitive impairment. Expediency of complex treatment of patients with chronic cerebral ischemia when combined hypertension and early manifestations of atherosclerosis in high cardiovascular risk with the use of aspirin and pentosanu polisulfatu under mandatory control of bleeding complications, has been proven.

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