Pryimenko A. Synthesis, transformations, physico-chemical and biological properties of 3,7-dihydro-1H-purine-2,6-dione derivatives

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U003471

Thesis Registration Form

0413U003471.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

30-05-2013

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The thesis deals with searching for the new highly effective and low toxic compounds with antioxidant, diuretic, neurotropic, anti-inflammatory, analgesic, spasmolytic, cholesterol-lowering activity amongst derivatives of 3,7-dihydro-1H-purine-2,6-dione and its condensed analogues. New preparative methods for synthesis of novel 3-methyl- and 1,3-dimethyl-8-R-1Н-purine-2,6(3Н,7Н)-diones, 3,7,8-; and 1,3,7,8-substituted and condensed 3,7-dihydro-1H-purine-2,6-dione derivatives were proposed.

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Files

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