Morar I. Elaboration of prognostic criteria of acute destructive pancreatitis (experimental and clinical study).

Object - dynamics of acute destructive pancreatitis in experimental and clinical; purpose - to improve the outcomes of patients with acute destructive pancreatitis by developing an algorithm surgical treatment, taking into account the impact of intra hypertension disease; methods - general clinical, biochemical, microbiological, morphological, tools, ex-mental, pathology and morphological; results - a method of modeling acute destructive pancreatitis in small laboratory animal that is introduced intrapancreatitis 10% solution of calcium chloride, the effectiveness of which is morphologically and biochemically proven for the first time discovered that the course of acute destructive pancreatitis complicated by the development of intra- hypertension, experimentally proven positive effects abdominal decompression on the dynamics of biochemical parameters of blood serum and microbial contamination of internal organs for acute destructive pancreatitis was first established that intra hypertension stages III-IV leads to dilated hyperemia, accompanied by degenerative-dystrophic and destructive changes internal organs, their swelling and subsequent development of multiple organ failure; branch – medicine.