Zharkova A. Ischemic heart disease, associated with acid peptic disease: the influence of antisecretory therapy on the homocysteine level and lipid spectre

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U005137

Thesis Registration Form

0413U005137.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

25-06-2013

Specialized Academic Board

Д.17.600.02

Essay

The thesis is presented for the Scientific Degree of Medical Sciences in the internal medicine specialty. The dissertaion is devoted to the study of the correlation between vitamin B12 serum level, hyperhomocysteinaemia and dyslipidemia in associated pathology (ischemic heart disease and acid peptic disease according to long-term proton pump inhibitor use) patients. During research there were discovered the significant prevalence of dyslipidemia, the lowest vitamin B12 serum level and the highest homocysteine serum level have been registrated in patients with combination of ischemic heart disease and acid peptic disease according to long-term proton pump inhibitor use. It was shown evident correlation between that changes and dyslipidemia. Тhe complex therapy that includes parenteral B12 supplementation leads to more effective correction of hyperhomocysteinaemia and dyslipidemia in patients with comorbidity of ischemic heart disease and acid peptic disease with long-term use of proton pump inhibitors.

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Files

Жаркова_Автореферат.doc

Жаркова_Дисертація.doc

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