Ternitskaya Y. Computed tomography and magnetic resonance imaging in the differential diagnostics of nasal cavity, paranasal sinuses diseases.

426 patients were investigated with the purpose to determine the potential of SCT and MRI in the differential diagnostics of nasal cavity and paranasal sinuses diseases: 175 patients - with nasal cavity and paranasal sinuses neoplasm (including 122 patients with malignant tumors); 171 - with inflammatory diseases, and 80 patients formed control group (absence of pathologic changes in sine-nasal part after head and neck SCT and MRI investigation data). The influence of separate and joint variants of paranasal sinuses structure at chronic rhinosinusitis incidence was stated; radiation semiotics of inflammatory processes and tumors of given localizations was systematized. SCT and MRI semiotics and differential diagnostics sighs of rhinosinusitis and nasal cavity and paranasal sinuses neoplasm were systematized. Informativeness indices of radiation diagnostics for inflammatory processes: accuracy - 98.1%, sensitivity - 97.0%, specificity - 99.2% (SCT); accuracy - 99.2%, sensitivity - 98.4%, specificity - 99.6% (MRI) and for benign and malignant tumors: accuracy - 89.7%, sensitivity - 94.3%, specificity - 85.1% and accuracy - 89.3%, sensitivity - 93.2%, specificity - 83.7% (SCT); accuracy - 89.7%, sensitivity - 94.3%, specificity - 85.2% and accuracy - 88.5%, sensitivity - 91.7%, specificity - 83.6% (MRI) were stated. For the first time the degree and peculiarities of sine-nasal part tumor blood supply were evaluated with MDCT-perfusiongraphy quantitative index and the technology of two-stage personalized MDCT-angiography was applied. It was suggested and introduced the new method of MDCT-image quantitative postprocessing by its heterogeneity coefficient that enabled to improve the total diagnostic accuracy up to 98.1-98.7%.