Myshchenko V. A targeted search for anticonvulsant substances from herbs of the Solanaceae family

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U007239

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

29-11-2013

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The thesis is devoted to the search for the new prospective herbal substances with the anticonvulsant activity from herbs of the Solanaceae family. Content of the main groups of the biologically active substances in the aerial parts of herbs of the Solanaceae family and their extracts is determined. Level of the anticonvulsant activity of aqueous, aqueous-alcohol and alcohol extracts from the aerial parts of herbs of the Solanaceae family is determined on the model of the pentyltetrazole convulsions at the animals. Correlation of dependence of anticonvulsant activity indexes from the content of flavonoids was discovered.

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