Lebedynska M. Clinical-and-immunological aspects and changes of quality of life in patients with community-acquired pneumonia and concomitant chronic heart failure

Under the supervision of 146 patients was: core group - 77 patients with community acquired pneumonia (CAP) and chronic heart failure (CHF), the second group - 39 patients with community acquired pneumonia, the third group - 30 patients with CHF. All groups were compared by gender, age, by body mass index. Presence of heart failure in patients with CAP leads to increassng of the frequency of complaints of breath's shortness, breath rate and heart rate compared with an isolated incident. In turn, the presence of CAP in patients with chronic heart failure is associated with an increased frequency of complaints of shortness of breath, heart rate, percentage of band neutrophils and ESR compared with isolated CHF. Feature of the flow of CAP patients with CHF is elevated levels of CRP in serum in onset of disease compared to patients without CHF that persists after 48-72 h. of treatment. After 48-72 hours. from the beginning ABT content CRP in patients with CAP and CHF exceeds the concentration of CRP in patients with CAP without CHF, despite the fact that the content of CRP during the first 2-3 days of treatment is reduced in patients with CAP (both CHF and without it) and remained unchanged in patients with chronic heart failure without incident. The presence of heart failure in patients with CAP compared with patients without heart failure has a negative impact on all sides of QOL, except as physical problems in limiting the life that stem from problems of health state for the last 4 weeks. The flow of QOL in CAP patients with CHF more difficult compared with patients without CHF, which documented lower rates of CAP and respiratory index scale throughout the observation period. QOL in patients with comorbidity compared with patients without CHF recovers slowed, as indicated by the appearance of significant differences in terms of the scale being 48-72 hours and 7 1 from the beginning of hospitalization