Scherbyna R. Synthesis, transformation, physico-chemical and biological properties of 2-(4H-1,2,4-triazole-3-ylthio)acetaldehydes

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U000587

Thesis Registration Form

0414U000587.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

28-02-2014

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The basic aim of this work is finding new high-level and low-toxic agents with antimicrobial, neuroprotective, antipyretic, analgesic, actoprotective, hypocholesterolemic, hypotriglyceridemic, diuretic on the hyperlipidemia background, anxiolytic and analeptic action among derivatives of 2-(4-R1-5-R-4H-1,2,4-triazolo-3-ylthio)acetaldehydes, establishment of regularities between chemical structure of synthesized compound and biological activity, selection and recommendation most active compound for preclinical trial.

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