Biliy A. Synthesis, transformation, physico-chemical and biological properties of 5-substituted 2-heteryl[1,2,4]triazolo[с]quinazolines

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U001900

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

29-04-2014

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

In this work we described new methods of synthesis, physico-chemical and biological properties of 2-heteryl-[1,2,4]triazolo[1,5-с]quinazolines, [2-(3-heteryl-[1,2,4]triazol-5-yl)phenyl]amines, S-derivatives of 2-heteryl-[1,2,4]triazolo[1,5-с]quinazolin-5(6Н)-оnes(thiones). New methods of synthesis for 2-heteryl-[1,2,4]triazolo[1,5-с]quinazolines, [2-(3-heteryl-[1,2,4]triazol-5-yl)phenyl]amines, 2-heteryl-[1,2,4]triazolo[1,5-с]quinazolin-5(6Н)-оnes(thiones) and theirs functional derivatives were proposed. The structures, physicochemical and biological properties of mentioned compounds were described.

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