Maydannyk O. Prognostication of preterm delivery for pregnant with high psychoemotional tension

The present thesis work explains the way to reduce the level of preterm birth among women who experience high level of psycho-emotional stress by detection of pregnant women who are at high risk of pathology development along with psychological care provision. The study revealed that 76,2 % of women who are at high risk of preterm birth live in stressful environment. Major amount (around 64 %) of pregnant women in study group stated that they live in terms of chronic stress. 36 % of pregnant women who had the clinical picture of preterm birth threat experienced psychological stress, which they defined significant. According to the research, the transformation of neuroendocrinal homeostasis proves that psycho-emotional stress plays a dominant role as a prognostic factor - the identified transformations considered typical for pregnancy with clinical signs of preterm birth threat connected with stress. A laboratory study defined that women who were under the threat of preterm birth, experienced a high level of trait anxiety and depressive disorders that caused a significant reduction in the compensatory reactions of cardiovascular, autonomic systems and neurohumoral regulation links. There was also defined, that psycho emotional tension caused the body immune system suppression, activating infectious-inflammatory process that often became the cause of preterm birth. It was conducted deep research of psychological status and laboratory diagnostics of the state of the immune system. Coming from the got results, a conclusion is done about considerable influence of psychoemotional tension during pregnancy on the immune system, violation of work of which is one of reasons of premature births.