Research object: process management inter-firm relations of enterprises in the supply chain; the purpose of the work: the improvement of theoretical positions, development of methodology and practical guidance for the management of inter-firm relations in the supply chain; methods and instruments: structural-logical analysis, synthesis and logical generalization, expert estimation, additive convolution, matrix methods, method of constructing a decision tree, scenario approach, the tools of the theory of fuzzy sets; theoretical and practical results: conceptual provisions to the management of inter-firm relations in the supply chain, which, unlike others, including implementation of the three-stage process: the formation of an integrated group of companies, the formation of the elements of the management system inter-firm relations, development of inter-firm relations, and are based on the worth approach, that allows to organize the sequence of steps in the process of formation and development of relations between the partners; methodical approach to assessment of the value of inter-firm relations, the feature of which is the inclusion of monetary and non-monetary worth, the choice of scenario inter-firm relations, using a matrix method allows to choose the most attractive partners; methodical approach to the formation of the integrated group of companies, the difference from existing consists in developing the most appropriate of the integration of decisions on establishing relations with potential partners on the basis of a method of constructing a decision tree, which allows to reduce expenses of time and money in search of partners; methodical support of development of elements of a control system inter-firm relations, which unlike the existing, provides for the definition of the types of the Central subject of management and species of the coordinating centre, the alignment of goals in integrated group, the distribution of responsibilities in the organizational structure considering scenarios inter-firm relations, allowing partners to implement control functions in accordance with their values in the chosen scenario; the content of the notion of «inter-firm relations» at the expense of its definition as relations between the enterprises, directed on the receipt of their values and determine the processes of interaction between participants, acquiring a certain form; methodological guidelines on the development of inter-firm relations, the difference of which is to use the value approach when defining development priorities that allows sound to choose the direction of development of inter-firm relations; subject and degree of introduction: developments are put in practical activity of «Turboatom», «Ukrhydroproject», «Electrotyazhmash», «Energyregulator», NTU «KHPI» for the master's degrees of specialties «Basics of foreign trade activities», «International marketing»; Scope: Management intercompany relationships in the supply chain through the introduction of a holistic approach.