Bdyuleva A. Features of pregnancy, childbirth and neonatal status in women with chronic hepatitis C in the background of HIV infection.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U004814

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

24-10-2014

Specialized Academic Board

Д 26.613.02

Essay

Science is devoted to reducing the risk of vertical transmission of HCV incidence and neonates born to mothers with chronic hepatitis C in the background of HIV infection, by optimizing clinical examination of pregnant women and early initiation of highly active antiretroviral therapy16 weeks pregnant. The author found that the presence of concomitant chronic hepatitis C in women with HIV infection aggravates during pregnancy increases the risk of complications such as oligohydramnios, placental insufficiency, growth retardation, anemia, preterm labor, which requires additional obstetric surveillance, special relationship with the planning and management of pregnancy in this category of women. For a more accurate prediction of the probability of vertical transmission of HCV in this group of women is necessary to determine the viral load (VL) of HCV quantitative method, with VL >2 106 copies/ml pregnant should be attributed to an increased risk of prenatal transmission of HCV. Earlier initiation of HAART (from 16 weeks of pregnancy) in pregnant women with chronic hepatitis C in patients with HIV infection reduces not only the risk of prenatal HIV infection of the fetus, as well as helping to reduce the HV HCV, there by warns vertical transmission path in this category of women.

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