Kharytonova O. Complex therapy of male patients with rosacea considering clinical-morphologic, psycho-somatic aspects and concomitant pathology

Object of study - rosacea. The aim - to improve the efficiency of treatment of men with rosacea by developing a complex differential treatment on the basis of the definition of clinical and anamnestic characteristics of flow and immunomorphogonesis of dermatosis. Methods: clinical, morphological, immunohistochemical, statistics. The thesis is devoted to the issues of increasing efficiency of treatment of male patients with rosacea based on a profound investigation of clinical-anamnestic peculiarities, immune morphogenesis of dermatosis in dynamics of treatment, using VEGF. There were examined 110 adults male patients with erythematous and papula-pustular forms of rosacea. There were defined peculiarities of clinical-morphologic and immune-histochemical markers of the disease in dependence with patients' age, type of the skin, clinical stage, concomitant pathology, psycho-somatic shifts and life quality. A new complex pathogenetic therapy of rosacea, depending on clinical form of the disease was proposed, its efficacy in comparison with traditional therapeutic methods was proved. The results of the work put into practice the Crimean Republic institution "Clinical Skin and Venereal Dispensary" (Simferopol), SE "Crimea State Medical University named after S.I. Georgievsky", MI "Zaporizhzhya Regional dermatovenerologic dispensary" of Zaporizhzhya regional council, SHEI "Ivano-Frankivsk National Medical University", MI "Ivano-Frankivsk regional clinical dermatovenerologic dispensary", MI "Odessa Regional dermatovenerologic dispensary", HSEI "I.Ya. Horbachevsky Ternopil State Medical University". Area of use - dermatology.