Hamoudi E. Optimization of urogenital diseases treatment associated with ureaplasma infection, with the account of the vaginal biotope

The object of study - urogenital diseases associated with ureaplasma infection. The purpose of research - improving the effectiveness of treatment of urogenital diseases associated with ureaplasma infection in women of reproductive age, based on the study of indicators of vaginal biotope and hormonal status by using a combination of local probiotic. Methods: clinical, microscopic, microbiology, molecular biology, immunoenzyme, biochemical, statistical. The thesis is devoted to the actual problem of dermatovenerology - improving the effectiveness of treatment of urogenital diseases associated with ureaplasma infection, through the development of a complex method of treatment using a combination of local probiotic, based on the study of the hormonal status and indicators of habitat of vagina. Hormonal disorders are one of the pathogenic mechanisms that lead to changes in the vaginal biotope, creating the conditions for enhanced development and active life Ureaplasma spp. The efficiency of the local destination probiotic combined with estriol, which helps to normalize indicators vaginal biotope by exogenous addition of lactic acid bacteria and maintain adequate estrogen saturation has been proved. Results of the study are introduced into the practice of MCTPI "City skin and venerologic dispensary of Donetsk", MCTPI HC "Regional dermato-venerologic dispensary" (Donetsk), SE "Institute of Dermatology and Venereology of NAMS of Ukraine." The results have been implemented in the educational process of the department of dermatovenerology of Donetsk National Medical University named after Gorky. Area of use - dermatology.