Vladov S. Methods and means for determining hemodynamic parameters in diagnosing disorders of the human blood circulation system

This dissertation substantiates the research methods for determining hemodynamic parameters when diagnosing functional disorders in certain areas of the human circulatory system, which is based a mathematical model of a human circulatory system as a heterogeneous coordinated long line with distributed variation parameters, which made it possible to improve the reliability of forecasting methods for further elimination of pathological processes in blood flow through the vessels: prompt surgical intervention, installation of a particular type of cava-filter (in case of a blood clot), prescription of therapy depending on the stage of a particular disease. Mathematical modeling of hemodynamic processes in the greater and lesser, cerebral and coronary circulation circuits using the developed model allowed us to obtain analytical expressions to describe how a pulse wave signal passes through a particular vessel, which made it possible to develop a method for verification determine the degree of damage caused to a certain section of the human circulatory system by the most common pathological processes in movement of blood through the vessels. The main results of the work have been implemented in Kremenchug Regional Hospital for Disabled Veterans in Poltava region for diagnosing patients with symptoms of hypertension, aortic stenosis, ischemic stroke and coronary heart disease.