Bigdan O. Synthesis, physico-chemical and biological properties of derivatives of 1,2,4-triazole-3-thiones, containing fluorinephenyl substituents

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U002529

Thesis Registration Form

0415U002529.pdf

Applicant for

Bigdan Oleksiy Antonovych

Specialization

15.00.02 - Фармацевтична хімія та фармакогнозія

Date of defense

28-05-2015

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

The aim of this work is the synthesis of new low-toxic and highly effective substances – 5-fluorinephenyl derivatives 1,2,4-triazole-3-thiol with potential antimicrobial, antifungal, antiviral, actoprotective, analgetical, antihypoxic, hypoglycemic, neuroleptic and analeptics activity, the establishment of relationships between chemical structure and biological activity of the synthesized compounds and recommendations for preclinical trials of the most promising compounds of the specified number.

Thesis supervisor

Panasenko Oleksandr Ivanovych

Official opponents

Омельянчик Людмила Олександрівна
Петюнін Геннадій Павлович

Files

aref.docx

dis.pdf

Similar theses

0523U100273

Lozynskyi Andrii V.

Polyfunctional condensed and non-condensed thiazole/thiazolidinone derivatives: directed synthesis, physicochemical properties and biological activity

0523U100081

Safonov Andrii A.

Синтез, перетворення, фізико-хімічні і біологічні властивості похідних 1,2,4-триазолу, які містять тіофен-2-ілметильний замісник

0523U100030

Bihdan Oleksii A.

Synthesis, chemical modification and biological properties of 3-, 4, 5-trisubstituted-1,2,4-triazole-3-thions

0521U101625

Borodina Nataliia Valerivna

Pharmacognostic study of willow plants and creation of medicines based on them. Qualifying scientific work on the rights of the manuscript

0421U102935

Anosova Liydmila Sergееvna

Chemical and toxicological study of clopidogrel