Kharchenko O. Hygienic assessment of the biometal citrates obtained by water-based nanotechnology

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U003156

Thesis Registration Form

0415U003156.pdf

Applicant for

Specialization

  • 14.02.01 - Гігієна

16-04-2015

Specialized Academic Board

Д.26.604.01

Essay

The thesis is dedicated to the hygienic assessment of modern technology products, conventionally called zinc N-citrates, magnesium and iron. The methodology and the algorithm were developed in it for the study of these compounds which are based on examination of the physical process of obtaining them. In accordance with it, chemical analogues were selected for the new compounds. Also selected, processed, and modified the appropriate methods of metals N-citrate and ion citrate constituents' analysis. A screening method was proposed for assessing their safety as nanotechnology products. It was shown that N-citrates are characterized by high chemical purity. A comparative study evaluated their acute toxicity and also of the biological action of N-citrates, salt citrates (X-citrate), and sulfates of these metals. A bioavailability of metals from these compounds is determined by a degree of their accumulation in the body and target tissues of laboratory animals.

Read more

Files

Автореферат.doc

Дисертація останній варіант.doc

Similar theses

0524U000130

Valentyna V. Chorna

Hygienic assessment of health care facilities for providing psychological and psychiatric care to the population in the pre-war period and under martial law

0521U101962

Zazulyak Tetyana Stepanivna

Improvement and harmonization of the system of hygienic regulations on the permissible concentration of chemical substances in workplace air with the European legislative framework in the case of pharmaceutical production

0521U101966

Andrushchenko Tetyana Anatoliivna

Genetic markers of DNA repair effectiveness under the influence of occupational factors

0421U000101

Kovalchuk Mariia Petrivna

Scientific rationale of measures for prevention of negative influence of outdoorair on the incidence of bronchial asthma in children of Kyiv

0421U000092

Chaika Anna Volodymyrivna

Hygienic assessment of the conditions of placement and operation of health care facilities built into residential buildings