Aliieva F. Differentiated approach to the diagnostics and treatment of inflammatory diseases of the cervix at various life stages

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U003260

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

26-12-2014

Specialized Academic Board

Д 26.613.02

Essay

The research paper aims at reducing the number of relapses and increasing the treatment efficiency for inflammatory diseases of the cervix at various life stages based on a differentiated approach to the choice of diagnostic, therapeutical and preventative measures designed to improve the local immune defence and the reparative processes in the endocervix. The author has investigated the pathological mechanisms for the development of inflammatory diseases of the cervix. Based on the data obtained, the author has provided a scientific justification for the concept associated with the role of mucous membrane defects in the pathogenesis of inflammatory diseases of the cervix, as well as their correction at various life stages. The author has demonstrated the implications of mucosal defects as abnormalities in the epitelial and the immunoeffector chains of local defence, microbial biocenosis, and a permanent pH shift. The author has proved the changes in the content, correlation and interrelation of gonadotropic and ovarian hormones, which cause adaptive stress condition and disregulation in teenage girls with their immature reproductive systems. A new approach to the correction of local hormonal disorders has been developed and scientifically justified. The above is based on the fundamental principle of correcting the defects detected by restoring the protective properties of mucous membranes and the hormonal homeostasis in teenage girls suffering from inflammatory diseases of the cervix. To correct the defects detected, low-frequency ultrasound was used, its effect being based on the interaction between mechanical oscillations, physical, chemical and neuroreflectory effects, and the effect of heat produced in body tissues while absorbing the ultrasound. This effect is realized in reproductive organs.

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