Sushko O. Nanophotonic method and sensor system for biologically active carcinogenic substances detection in liquid-phase medium

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U003993

Applicant for

Specialization

  • 05.11.17 - Медичні прилади та системи

02-07-2015

Specialized Academic Board

Д 64.050.17

National Technical University "Kharkiv Polytechnic Institute"

Essay

The object of research is the processes in semiconductor quantum-dimensional structures of nanophotonic sensor system in the liquid phase medium with organic carcinogens which are accompanied by the flow of electric current and optical emission analytical signal. The purpose of the dissertation work is the development and experimental testing of nanophotonic method and sensor system with low detection limit and high speed of biologically active carcinogens detection in liquid-phase environments such as bioliquids and environmental objects. Research methods are modeling with use of quantum mechanics instruments and measurements theory, experimental investigation of samples, statistical result manipulation. Theoretic and practical results - carcinogenic pollutants were defined; known methods and advantages of nanophotonic method were analyzed; practicability of quantum dots use was proven; mathematic modeling of processes in system was carried out; the sensing device and sensor system were developed and investigated; the method of 3,4-benzopyrene detection was developed. The novelty - nanophotonic method for 3,4-benzopyrene detection was used for the first time. The analytical signal generation was investigated for the first time. The theoretic investigation of processes in system measuring channel was carried out for the first time. The concept of system sensing device was upgraded which are differs by the use of the quantum dots as detector. The implementation level - Department of Phthisiology and Pulmonology in KhMAPE, Biomedical Engineering Department of KhNURE. Application - biomedical engineering, laboratory analysis.

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