Bahriy V. Uncomplicated essential hypertension in women, clinical polymorphism diagnostic value of gene PPAR-gamma and plasma conctntration vasomotor peptides

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005568

Applicant for

Specialization

  • 14.01.11 - Кардіологія

02-10-2015

Specialized Academic Board

Д 20.601.01

Ivano-Frankivsk national medical university

Essay

Among postmenopausal women, 101 hypertensive patients almost twice more common allele Ala allele and less Pro gene PPAR-gamma has obtained. In stage II hypertension vascular natriuretic peptide (CNP) level was higher than in hypertension stage I and not associated with genotype gene PPAR-gamma. The concentration of endothelin-1 was higher in hypertension stage II than in stage I hypertension. Inheritance genotype Pro/Pro hypertension associated with more pronounced changes in structural and functional parameters infarction. Diastolic dysfunction and express the degree of left ventricular hypertrophy is accompanied by higher concentration in plasma vascular CNP. Branch - medicine.

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